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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
24.85
Human Site:
S1161
Identified Species:
49.7
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
S1161
K
E
D
S
V
S
Q
S
S
S
D
A
G
L
G
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
S1161
K
E
D
S
V
S
Q
S
S
S
D
A
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
G104
F
L
G
H
N
G
A
G
K
T
T
T
M
S
I
Dog
Lupus familis
XP_538773
2261
253895
S1161
K
E
D
S
V
S
Q
S
S
S
D
A
G
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
S1161
K
E
D
S
V
S
Q
S
S
S
D
A
G
L
G
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
S1131
Y
A
G
A
L
D
G
S
F
A
T
V
F
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S1165
K
E
D
S
V
S
Q
S
S
S
D
A
G
L
G
Chicken
Gallus gallus
NP_989476
2260
254054
S1161
K
D
D
S
V
S
Q
S
S
S
D
A
G
L
G
Frog
Xenopus laevis
NP_001089022
2363
267334
P1258
C
P
C
A
S
C
T
P
K
A
K
E
D
P
L
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
K1241
C
S
T
C
T
R
Y
K
E
E
S
Q
A
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
R728
V
E
R
E
K
A
N
R
T
I
L
L
T
T
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
S906
I
G
S
N
Q
K
S
S
M
Q
P
K
L
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
6.6
N.A.
100
93.3
0
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
26.6
N.A.
100
100
13.3
6.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
9
9
0
0
17
0
50
9
0
9
% A
% Cys:
17
0
9
9
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
50
0
0
9
0
0
0
0
50
0
9
0
0
% D
% Glu:
0
50
0
9
0
0
0
0
9
9
0
9
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
9
17
0
0
9
9
9
0
0
0
0
50
0
50
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% I
% Lys:
50
0
0
0
9
9
0
9
17
0
9
9
0
0
0
% K
% Leu:
0
9
0
0
9
0
0
0
0
0
9
9
9
67
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
9
0
0
9
0
0
9
0
% P
% Gln:
0
0
0
0
9
0
50
0
0
9
0
9
0
9
9
% Q
% Arg:
0
0
9
0
0
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
9
9
50
9
50
9
67
50
50
9
0
0
9
0
% S
% Thr:
0
0
9
0
9
0
9
0
9
9
17
9
9
9
0
% T
% Val:
9
0
0
0
50
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _